The chemistry of gut microbiome in health and diseases

There are trillions of microbes residing in our body, with their collective genomes much more than human genomes. They have been living a close relationship us and play role various biological functions. The begin to build up utero, accumulate, fluctuate until set point is achieved around three years age. gut microbiome altered by several factors, which include age, diet, antibiotic use. After the exposure, microbe may shift back retain its balance, but some factors leave permanent footprint on flora. This be significant as review has shown relationships between diseases. When homeostasis gut-microbes disrupted, multiple mechanisms contribute diseases' development. balance protective pathogenic must kept check prevent disease onset. With better understanding this relationship, we will investigate potential methods modify flora background developing therapeutic options. already options such prebiotics, probiotics, fecal transplantation, clinical use limited restricted. Therefore, there still need characteristic association gut-dysbiosis-related diseases, help manage develop diagnostic monitoring tools. aims discuss health